I wasn't a particular fan of the VHS-effect, but the animation was surprisingly smooth and the lip-syncing was done very well.
In terms of story: The fact that many of the people depicted were either extraterrestrials or robots was not 'lost' on me, but I feel that that the deeper meaning behind that could have been incorporated better into the animation to make the sketch more 'your own'. The reactions of the alienated kids were a good step, but I would have preferred a bit more 'Transformative Use', if you will. ;)
I am usually not a fan of animation made as animation for a professionally produced scene that already exists (or some YouTubers). It's borrowed/transplanted humor so even if the animation compliments it nicely, it usually feels like a lesser version of the original. Although you did a good job this is also the case here.
But that being said...: "Dude, that was a _superb_ choice of audio!" The sketch is from 1997, so unlike animations set to a conversation of popular YouTubers that happened 1 to 3 months ago, most of the people who are going to see this will be unfamiliar with it when they first watch it - or it has been so long that only vaguely remember the original.
But above all else: The timing for the release could hardly have been better. This very much reflects what an international audience expects when an elected official from the US steps in front of a microphone for the next 4-ish years.
I would have preferred if the video had credits, so it would be a bit harder for others to claim that 'they' have made this. Not just your name/online handle but also the credits for the original audio. At the time of writing, the description only credits the source as "Original Audio: Mr. Show".
You have lots of space to spare. My non-committal recommendation would be something that looks like this:
"Original Audio: Mr. Show with Bob and David (Series, 1995 to 1998), (S03E06: Goin' on a Holiday) (1997) (Sketch: 'Blowing Up The Moon')"
The description could also have a link to the website where you've got it from or at least a Wikipedia/IMDB-link embedded (like this: https://en.wikipedia.org/wiki/Mr._Show_with_Bob_and_David#Season_3_(1997) )
One last thing of note in terms of presentation would be the tag situation. You used #comedy, but it's already in one of the two Comedy categories on Newgrounds, so that seems a little redundant. And you are using #animation... On a website that hosts 99.x% animations in their Movie Portal. I'm sure you can do better. (You have a limit of 12 tags.)
Which tools you used would also be helpful information for other animators.
I hope this helps.